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当前位置:药品说明书与价格首页 >> 眼科 >> 干眼症 >> 药品推荐 >> 环孢素滴眼液|Restasis(Cyclosporine Eye Drops)

环孢素滴眼液|Restasis(Cyclosporine Eye Drops)

2012-05-29 20:08:06  作者:新特药房  来源:中国新特药网天津分站  浏览次数:0  文字大小:【】【】【
简介: 英文药名: Restasis(Cyclosporine Eye Drops) 中文药名: 环孢素滴眼液 品牌药生产厂家: Allergan 药品名称 【药品名称】 通用名称:环孢素滴眼液 英文名称:Cyclosporin Eye Drops 【性 状】本品为 ...

 英文药名: Restasis(Cyclosporine Eye Drops)

中文药名: 环孢素滴眼液

品牌药生产厂家: Allergan

药品名称

【药品名称】
通用名称:环孢素滴眼液
英文名称:Cyclosporin Eye Drops
【性 状】本品为淡黄色的澄明油状液体。
药品简介

阿勒干公司上市的0.05%环孢素眼用乳剂,商品名:Restasis。此具有消炎作用的局部免疫调节剂适用于因干燥性角结膜炎引起的眼内炎症抑制泪液产生,增加患者的泪液产生。
适 应 症

用于预防和治疗眼角膜移植术后的免疫排斥反应。
用法用量

本品仅进行了与糖皮质激素联合应用预防角膜移植术后免疫排斥反应的临床试验,对本品单独应用预防角膜移植术后免疫排斥反应尚无临床数据支持。
在与糖皮质激素联合应用时本品的用法用量为:将药物滴入结膜囊内,每日4-6次,每次1-2滴。
本品临床应用根据治疗疾病的种类不同, 用量有一定差异, 必须在专业医师的指导下或遵医嘱用药。
使用方法:因本品为油溶液,使用时旋开瓶盖,将滴眼瓶与眼部垂直,轻轻挤压滴眼瓶,使药液滴入眼内,避免药液挂流瓶口造成污染,用完后立即盖好瓶盖。
不良反应

本品的临床试验过程中有部分患者出现眼部轻微刺激症或结膜轻度充血,有报道偶见睫毛脱落、角膜上皮缺损、眼周皮炎、过敏症、角膜上皮点状病变等症状,但停药后可自愈。
禁 忌

对环孢素过敏者、对滴眼液中其他成份过敏者。
注意事项

1. 角膜移植术后如发生植片排斥反应,临床医生可视排斥反应的轻重不同适当增加本品滴眼次数。
2. 与糖皮质激素联合应用时请注意逐渐调整糖皮质激素的给药剂量。
3.本品不具有抗感染功效,若发生感染,应立即用抗生素治疗。
4.本品放置儿童不易拿到的地方。儿童用药须在成人的监护下使用。
5.本品低温贮存时,有凝固倾向,可呈轻微凝固状或有轻微烟雾状或见少量絮状物,如果出现这些情况,使用时将本品放置在室温下(25-30℃),并轻微振摇直至其消失成溶液状。本品发生凝固状或烟雾状或少量絮状物并不影响药物质量。
孕妇及哺乳期妇女用药

本品口服可以通过胎盘,也可进入乳汁,对哺乳的婴儿可产生高血压、肾毒性、恶性肿瘤等不良作用的潜在危险性。眼局部用药仍有全身吸收,虽然浓度很低(<50 ng/ml),但尚不清楚是否可通过胎盘和通过人乳分泌, 所以孕妇及哺乳妇女避免使用。如必须使用,应在使用前排除妊娠的可能性,哺乳妇女不应哺乳。


 
规格:

0.05% 30个 x 0.4ml 眼药乳液
0.05% 1支 x 3ml 眼药水

 

Restasis - Prescription Eye Drops for Dry Eyes
Restasis is One Treatment for Dry Eyes but has Limitations Due to Side Effects and Cost
Restasis Ophthalmic Emulsion (cyclosporine ophthalmic emulsion 0.05%) by Allergan Pharmaceuticals is a prescription eye drop used for the treatment of chronic dry eye (keratoconjunctivitis sicca). Restasis is the only prescription eye drop medicine that is prescribed for long-term use to increase the eye’s ability to produce tears for patients whose tear production is suppressed due to ocular inflammation.

Dry eye syndrome is an ongoing condition and depending on its cause, it may not be curable but it can definitely be managed. There are different causes of dry eye. One cause in particular is ocular inflammation that suppresses the production of tears.

How Restasis Works
Patients with chronic dry eye have more inflammatory T-cells that produce by-products, which decrease the nerve signals to the lacrimal gland resulting in dryness.  Restasis inhibits the activation of T-cells, which results in increased tear production by the lacrimal gland.  Restasis does not improve tear flow in patients on anti-inflammatory eye drops or those with punctal plugs.

Recommended Dosage of Restasis
The recommended dosage of Restasis is one drop twice a day (1 drop in the morning and another drop in the evening approximately 12 hours apart).  The medication comes in a package of 30 (thirty) single use vials.  Some patients may begin to experience the benefit of increased tear production in as early as one month, but for others, it may take a few months longer since no two people react to the medication exactly the same. It is essential that Restasis be used consistently, twice a day, every day to achieve maximum effectiveness. Since there currently is no cure for chronic dry eye, Restasis is a long-term treatment and its benefits will cease if the product is discontinued.

Side Effects of Restasis
The most common side effect following the use of Restasis is ocular burning (17% of patients).  Other possible side effects (1-5% of patients) of Restasis include conjunctival redness, stinging, pain, foreign body sensation, itching and blurred vision. The use is contradicted with patients who have an active eye infection or for those who have a known or suspected hypersensitivity to any one of its ingredients. The safety and efficacy has not been established for patients under the age of sixteen.  There are also no well controlled or adequate studies for Restasis in pregnant women and caution should be exercised in nursing mothers.  Restasis should not be used while wearing contact lenses.

Cost of Restasis
Most patients with commercial health insurance have plans that cover most of the cost of RESTASIS® prescriptions. Most patient co-pays for a RESTASIS® prescription ranges from $20 to $50 for a monthly supply (2 trays).

Alternative Dry Eye Treatments
There are many solutions to improving chronic dry eye syndrome including therapy with Lotemax, Omega 3’s, punctal occlusion, artificial tears and doxycycline to name a few.  Restasis is one medical treatment that may be prescribed by your eye care doctor at Master Eye Associates.

环孢素滴眼液|Restasis(Cyclosporine Eye Drops)咨询

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