【药物名称】Ladakamycin(formerly), Azacitidine, U-18496, NSC-102816, Vidaza, Mylosar
【化学名称】5-Azacytidine; 4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 1-(beta-D-Ribofuranosyl)-5-azacytosine
一级分类：抗肿瘤药物 二级分类：其他 三级分类：
What is Azacitidine injection?
AZACITIDINE (Vidaza™) is a chemotherapy agent used to treat myelodysplastic syndromes and may be used to treat some types of leukemia. Azacitidine interferes with the growth of rapidly dividing cells, like cancer cells, and eventually causes these cells to die. Generic azacitidine injections are not available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
• dental disease
• infection (especially viral infections such as chickenpox or herpes)
• kidney disease
• liver disease
• an unusual reaction to Azacitidine, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
How should this medicine be used?
Azacitidine is given as an injection under the skin by a trained health care profesiional. It has also been given by an infusion into a vein. Azacitidine is usually administered in a hospital or clinic setting.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What drug(s) may interact with Azacitidine?
Talk to your prescriber or health care professional before taking any of these medicines:
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking Azacitidine?
Visit your prescriber or health care professional for checks on your progress. You will need to have regular blood checks. The side effects can continue after you finish your treatment; report side effects promptly.
Azacitidine may make you feel generally unwell. This is not uncommon because azacitidine affects good cells as well as cancer cells. Report any side effects as above, but continue your course of medicine even though you feel ill, unless your prescriber or health care professional tells you to stop.
Azacitidine may decrease your body's ability to fight infections. Call your prescriber or health care professional if you have a fever, chills, sore throat or other symptoms of a cold or flu. Do not treat these symptoms yourself. Try to avoid being around people who are sick. Azacitidine may increase your risk to bruise or bleed. Call your prescriber or health care professional if you notice any unusual bleeding. Be careful not to cut, bruise or injure yourself because you may get an infection and bleed more than usual.
Avoid taking aspirin, acetaminophen (Tylenol®), ibuprofen (Advil®), naproxen (Aleve®), or ketoprofen (Orudis® KT) products as they may mask a fever, unless instructed to by your prescriber or health care professional.
Be careful brushing and flossing your teeth or using a toothpick while receiving azacitidine because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving azacitidine.
There is a possibility that azacitidine could cause harm to an unborn child; this applies to both men and women. If you are pregnant or you or your partner are considering getting pregnant, talk to your health care provider about the risks of azacitidine therapy. Women or men whose partner may have children should use appropriate birth control methods during azacitidine therapy. Discuss possible methods of birth control with your health care provider.
If you are going to have surgery or dental work, tell your prescriber or health care professional that you are using azacitidine.
What side effects may I notice from receiving Azacitidine?
The side effects you may experience with azacitidine therapy depend upon the dose, other types of chemotherapy or radiation therapy given, and the disease being treated. Not all of these effects occur in all patients. Discuss any concerns or questions with your prescriber or health care professional.
Side effects that you should report to your prescriber or health care professional as soon as possible:
• low blood counts - azacitidine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.
• signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
• signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
• signs of decreased red blood cells - unusual weakness or tiredness, fainting spells, lightheadedness
• reactions at the injection site including redness, pain, itching, or bruising
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• loss of appetite
• nausea, vomiting
• skin rash, itching
• stomach pain
• water retention
Where can I keep my medicine?
This does not apply. You will only receive this medicine in a hospital or clinic setting and will not need to store it at home.
VIDAZA 100mg/Vial 10Vials/box
维达扎 100毫克/瓶 10瓶/盒